AlzChem Global
Guanidine Salts for biotechnological, diagnostic and pharmaceutical applications

Guanidine Salts

Based on the raw material dicyandiamide, also manufactured by AlzChem, a range of guanidine salts are also produced. These are often used as NCN building blocks for the synthesis of Pyrimidines, and other intermediates which are indispensable in the production of agro-chemicals and pharmaceutical active ingredients, for instance.

Guanidine nitrate and nitroguanidine (which is manufactured from guanidine nitrate by our sister company NIGU Chemie GmbH) are used as gas generators in airbags.

Guanidine hydrochloride is used in a purified form for isolation and column cleaning during the production of monoclonal antibodies or recombinant proteins. Alongside the technical-grade quality produced by AlzChem, highly purified biotec grades are also on offer, produced by the company NIGU Chemie GmbH.
There are further applications for guanidine hydrochloride in electroplating and in textile treatment.

Guanidine thiocyanate is also offered by Nigu as support material for the isolation of nucleic acids and for RNA/DNA (clinical) diagnostics.

Guanidine phosphate and guanidine sulfamate are used as additives and flame retardants in, for example, the production of laminates (e. g. kitchen work-surfaces)

Verena Schwarzer

Verena Schwarzer

T +49 8621 86 2622


AlzChem AG offers exclusive customized service when it comes to Guanidine Hydrochloride and Guanidine Thiocyanate: We prepare custom-made buffer solutions for biotechnological application – starting with small scale production.
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In response to the high demands of the pharmaceutical Industry, Alzchem also offers a premium pharmaceutical grade quality of Dicyandiamide named TROPHARM.  Working hand-in-hand with our pharmaceutical customers we have developed various customer specific tailor-made grades of extreme high purity and exceptional low levels of impurities and water content. TROPHARM is a major component in the manufacture of Metformin, an API used for the treatment of diabetes.
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A special technology established at AlzChem is the use of sodium borohydrate for reductions in technical scale. The compound is an efficient and selective reducing agent for a series of organic molecules. AlzChem has appropriate equipment and suitable processes for a safe application and knows how to handle this challenging reagent.
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AlzChem exhibited at the 5th Specialty & Agro Chemicals America show September 9-11 at Charleston, SC. The exhibition continues to grow as a very fast pace and has become the most important event to reach our target audience in the US. AlzChem presented the NCN- and nitriles chemistry and had fruitful discussions with a large number of US customers.  Progress in several projects made the show another success.
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31.05.2017 to 01.06.2017
Continuing a longstanding tradition, AlzChem will again be represented in 2017 with its own booth at ChemSpec Europe. The show will take place on May 31/June 01 in Munich. On top of our standard portfolio consisting of cyanamide, dicyandiamide...
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